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Gatifloxacin-d4 hydrochloride

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SL-8319

Gatifloxacin-d4 hydrochloride, >98%

CAS No. : [1189946-71-1]

Synonyms : AM-1155-d4 hydrochloride; BMS-206584-d4 hydrochloride; PD135432-d4 hydrochloride

IUPAC Name : 1-Cyclopropyl-6-fluoro-8-methoxy-7-(3-methylpiperazin-1-yl-2,2,6,6-d4)-4-oxo-1,4-dihydroquinoline-3-carboxylic acid hydrochloride

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Chemical Properites
Mol. Formula :
C19H18D4FN3O4 . HCl
Mol. Weight :
415.88
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is a deuterium labelled version of Gatifloxacin hydrochloride, which is a potent fluoroquinolone antibiotic with broad-spectrum antibacterial activity. Gatifloxacin hydrochloride inhibits bacterial type II topoisomerases and E. coli. Gatifloxacin hydrochloride eye drops are used to treat infections of the eye, such as bacterial conjunctivitis.

References : Takei M. et al.: Antimicrob Agents Chemother., 42(10), 2678-81, 1998; Fukuda H. et al.: Antimicrob Agents Chemother., 42(8), 1917-22., 1998; Yamada C. et al.: Eur. J. Pharmacol., 553(1-3), 67-72, 2006.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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