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GC-78 hydrochloride

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SI-7445

GC-78 hydrochloride, >98% (HPLC)

CAS No. : [3022242-53-8]

IUPAC Name : (S)-1-(3,4-Dichlorophenyl)-4-(4-methoxynicotinoyl)-N-(4-methoxyphenyl)piperazine-2-carboxamide hydrochloride

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C25H24Cl2N4O4 • HCl
Mol. Weight :
551.85
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GC‑78 hydrochloride potently inhibits SARS‑CoV‑2 Mpro (IC50 = 0.19 µM) and displays robust antiviral activity in cellular systems. Its nonpeptidic structure, oral bioavailability, and favorable pharmacokinetic profile highlight its relevance for studies of coronavirus protease inhibition.

References : Gao S. et al.: J. Med. Chem., 66(23), 16426-16440, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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