GDC-0310

SI-6245

GDC-0310, >98% (HPLC)

CAS No. : [1788063-52-4]

IUPAC Name : (S)-5-Cyclopropyl-4-((1-(1-(3,5-dichlorophenyl)ethyl)piperidin-4-yl)methoxy)-2-fluoro-N-(methylsulfonyl)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GDC‑0310 is an acyl‑sulfonamide NaV1.7 inhibitor with strong selectivity and sub‑nanomolar potency (IC₅₀ = 0.6 nM) for the human channel. It serves as a tool compound for probing NaV1.7 function in pain‑signaling pathways.

References : Safina S. B. et al.: J. Med. Chem., 64(6), 2953-2966, 2021; Xu L. et al.: Drug Discov. Today, 24(7), 1389-1397, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.