GDC-0349

SI-7376

GDC-0349, >98% (HPLC)

CAS No. : [1207360-89-1]

IUPAC Name : (S)-1-Ethyl-3-(4-(4-(3-methylmorpholino)-7-(oxetan-3-yl)-5,6,7,8-tetrahydropyrido[3,4-d]pyrimidin-2-yl)phenyl)urea

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GDC‑0349 is a selective ATP‑competitive mTOR inhibitor with strong potency (K_i= 3.8 nM). It blocks the activity of both mTORC1 and mTORC2 complexes, making it a valuable tool for dissecting mTOR‑regulated growth, metabolism, and survival pathways.

References : Pei Z. et al.: ACS Med. Chem. Lett., 4(1), 103-107, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.