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GDC-0853

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SI-909

GDC-0853, >98% (HPLC)

CAS No. : [1434048-34-6]

MDL No. : MFCD30489729

Synonyms : Fenebrutinib

IUPAC Name : (S)-2-(3’-(Hydroxymethyl)-1-methyl-5-((5-(2-methyl-4-(oxetan-3-yl)piperazin-1-yl)pyridin-2-yl)amino)-6-oxo-1,6-dihydro-[3,4'-bipyridin]-2'-yl)-7,7-dimethyl-3,4,7,8-tetrahydro-2H-cyclopenta[4,5]pyrrolo[1,2-a]pyrazin-1(6H)-one

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG95.00
Back Order  Estimated to ship on 01 November 2026
10MG155.00
Back Order  Estimated to ship on 01 November 2026
25MG255.00
Back Order  Estimated to ship on 01 November 2026
50MG395.00
Back Order  Estimated to ship on 01 November 2026
100MG665.00
Back Order  Estimated to ship on 01 November 2026
250MG1395.00
Back Order  Estimated to ship on 01 November 2026
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Chemical Properites
Mol. Formula :
C38H45N7O4
Mol. Weight :
663.81
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GDC-0853 is a potent, selective, and noncovalent bruton's tyrosine kinase (BTK) inhibitor with a Ki of 0.91 nM.

References : Crawford J. J. et al.: J. Med. Chem., 61(6), 2227-2245, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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