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Gemifloxacin mesylate

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Gemifloxacin mesylate, >98%

CAS No. : [210353-53-0]

Synonyms : Gemifloxacin (E)-isomer; Floxguard; Factive; SB-265805S; LB-20304a

IUPAC Name : (E)-7-(3-(Aminomethyl)-4-(methoxyimino)pyrrolidin-1-yl)-1-cyclopropyl-6-fluoro-4-oxo-1,4-dihydro-1,8-naphthyridine-3-carboxylic acid--methanesulfonic acid (1/1)

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Chemical Properites
Mol. Formula :
C18H20FN5O4 • CH3SO2OH
Mol. Weight :
485.49
Appearance :
Pale yellow solid
Melting Point :
Not available
Solubility :
DMSO
For Laboratory research use only, not for drug, household or other uses.

Applications : Gemifloxacin mesylate is a fluoroquinolone that acts as an effective anti-pneumococcal agent and is active against quinolone-resistant pneumococci. Gemifloxacin mesylate is used in research on respiratory infections like community-acquired pneumonia (CAP) and acute exacerbation of chronic bronchitis (AECB). The salt form, Gemifloxacin mesylate, has similar biological activity to the free compound but offers improved water solubility and stability.

References : Yoo B. K. et al.: Ann Pharmacother., 38(7-8), 1226-35, 2004; Davies T. A. et al.: Antimicrob Agents Chemother., 44(2), 304-10, 2000.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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