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Gemilukast

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SI-5045

Gemilukast, >98% (HPLC)

CAS No. : [1232861-58-3]

Synonyms : ONO-6950

IUPAC Name : 4,4'-(4-Fluoro-7-((4-(4-(3-fluoro-2-methylphenyl)butoxy)phenyl)ethynyl)-2-methyl-1H-indole-1,3-diyl)dibutyric acid

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Chemical Properites
Mol. Formula :
C36H37F2NO5
Mol. Weight :
601.69
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Gemilukast is an orally active and potent dual cysteinyl leukotriene 1 and 2 receptors (CysLT1 and CysLT2) antagonist, as a therapeutic agent for asthma.

References : Itadani S. et al.: J. Med Chem., 58(15), 6093-6113.2015; Yonetomi Y. et al.: Eur.J. Pharmacol., 765, 242-248, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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