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GFB-12811

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SI-6951

GFB-12811, >98% (HPLC)

CAS No. : [2775311-17-4]

IUPAC Name : (R)-1-(7-((5-Fluoro-2-(trifluoromethyl)pyridin-4-yl)amino)-1,6-naphthyridin-2-yl)-1-(1-methylpiperidin-4-yl)ethan-1-ol

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Chemical Properites
Mol. Formula :
C22H23F4N5O
Mol. Weight :
449.45
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GFB‑12811 selectively targets CDK5 with nanomolar potency (IC50 = 2.3 nM), making it a valuable tool compound for probing CDK5‑dependent processes in neurobiology and cancer research.

References : Daniels M. H. et al.: J. Med. Chem., 65(4), 3575-3596, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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