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Gilteritinib hemifumarate

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SI-5258

Gilteritinib hemifumarate, >98% (HPLC)

CAS No. : [1254053-84-3]

Synonyms : ASP2215 hemifumarate

IUPAC Name : 6-Ethyl-3-((3-methoxy-4-(4-(4-methylpiperazin-1-yl)piperidin-1-yl)phenyl)amino)-5-((tetrahydro-2H-pyran-4-yl)amino)pyrazine-2-carboxamide hemifumarate

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Chemical Properites
Mol. Formula :
C29H41D3N8O3 . 1/2C4H4O4
Mol. Weight :
610.76
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Gilteritinib hemifumarate is a potent and ATP-competitive FLT3/AXL inhibitor. It is used to treat relapsed or refractory acute myeloid leukemia.

References : Mori M. et al.: Invest New Drugs 35(5), 556-565, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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