Giredestrant

SI-6746

Giredestrant, >98% (HPLC)

CAS No. : [1953133-47-5]

Synonyms : GDC-9545; RG-6171

IUPAC Name : 3-((1R,3R)-1-(2,6-Difluoro-4-((1-(3-fluoropropyl)azetidin-3-yl)amino)phenyl)-3-methyl-1,3,4,9-tetrahydro-2H-pyrido[3,4-b]indol-2-yl)-2,2-difluoropropan-1-ol

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Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : Giredestrant is an orally bioavailable, non‑steroidal ER antagonist that binds competitively with estradiol and promotes a conformational rearrangement of the ER ligand‑binding domain. This mechanism underlies its strong anti‑tumor activity in estrogen‑dependent cancer models.

References : Metcalfe C. et al.: Cancer Res., 79(4), P5-04-07, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.