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GK-921

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SI-8166

GK-921, >98% (HPLC)

CAS No. : [1025015-40-0]

IUPAC Name : 3-(Phenylethynyl)-2-(2-(pyrrolidin-1-yl)ethoxy)pyrido[2,3-b]pyrazine

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Chemical Properites
Mol. Formula :
C21H20N4O
Mol. Weight :
344.42
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GK-921 inhibits human recombinant TG2 with micromolar potency (IC50 = 7.71 µM) and is suitable for studies exploring TG2‑dependent signaling, fibrosis, and inflammatory pathways.

References : Ku B. M. et al.: J. Cancer Res. Clin. Oncol., 140(5), 757-67, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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