Glibenclamide

SI-7455

Glibenclamide, >98% (HPLC)

CAS No. : [10238-218]

Synonyms : Glyburide

IUPAC Name : 5-Chloro-N-(4-(N-(cyclohexylcarbamoyl)sulfamoyl)phenethyl)-2-methoxybenzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Glibenclamide is an orally active KATP channel inhibitor that directly targets SUR1‑containing channels and inhibits P‑glycoprotein and CFTR. It alters mitochondrial ion permeability, leading to bioenergetic disruption, and is capable of inducing autophagy. These combined activities support its use in research on diabetes, obesity, and cellular‑stress pathways.

References : Heo R. et al.: Life Sci., 283, 119868, 2021; Qiu Y. et al.: iScience, 23(9), 101446, 2020; Golstein P. E. et al.: Pflugers Arch., 437(5), 652-660, 1999; Fernandes M. A. et al.: J. Biochem Mol Toxicol., 18(3), 162-169, 2024; Zhou J. et al.: Int. J. Endocrinol., 1265175, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.