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Glimepiride EP impurity A

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SL-5746

Glimepiride EP impurity A, >98%

CAS No. : [684286-46-2]

Synonyms : Glimepiride USP related compound A; cis-Glimepiride isomer

IUPAC Name : 3-Ethyl-4-methyl-N-(4-(N-(((1s,4s)-4-methylcyclohexyl)carbamoyl)sulfamoyl)phenethyl)-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamide

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Chemical Properites
Mol. Formula :
C24H34N4O5S
Mol. Weight :
490.62
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Glimepiride (Glimepiride EP impurity A), which is a potent Kir6.2/SUR inhibitor, belongs to the sulfonylurea class of drug, used in the treatment of type 2 diabetes mellitus.

References : Song D. K. et al.: Br. J. Pharmacol., 133(1), 193-199, 2001; Müller G. et al.: Horm Metab Res., 28(9), 469-487, 1996; Lawrence C. L. et al.: Br. J. Pharmacol., 136(5), 746-752, 2002; Rabbani S. I. et al.: Indian J. Exp Biol., 47(10), 804-810, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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