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Glimepiride EP impurity G

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SL-5754

Glimepiride EP impurity G, >98%

Synonyms : Glimepiride USP related compound G; Glimepiride N-methyl ester

IUPAC Name : Methyl ((4-(2-(3-ethyl-4-methyl-2-oxo-2,5-dihydro-1H-pyrrole-1-carboxamido)ethyl)phenyl)sulfonyl)(methyl)carbamate

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Chemical Properites
Mol. Formula :
C19H25N3O6S
Mol. Weight :
423.48
Appearance :
White to Off-white solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : This is an impurity of Glimepiride (Glimepiride EP impurity G), which is a potent Kir6.2/SUR inhibitor, belongs to the sulfonylurea class of drug, used in the treatment of type 2 diabetes mellitus.

References : Song D. K. et al.: Br. J. Pharmacol., 133(1), 193-199, 2001; Müller G. et al.: Horm Metab Res., 28(9), 469-487, 1996; Lawrence C. L. et al.: Br. J. Pharmacol., 136(5), 746-752, 2002; Rabbani S. I. et al.: Indian J. Exp Biol., 47(10), 804-810, 2009.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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