GLPG-1205

SI-7162

GLPG-1205, >98% (HPLC)

CAS No. : [1445847-37-9]

IUPAC Name : (S)-2-((1,4-Dioxan-2-yl)methoxy)-9-(cyclopropylethynyl)-6,7-dihydro-4H-pyrimido[6,1-a]isoquinolin-4-one

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GLPG-1205 potently and selectively antagonizes GPR84, shows good oral activity, and displays anti‑inflammatory effects relevant to pulmonary fibrosis. Its alkyne functionality allows CuAAC‑based conjugation with azide‑bearing molecules.

References : Sundqvist M. et al.: Biochim, Biophys Acta. Mol. Cell. Res., 1865(5), 695-708, 2018; Saniere L. et al.: American Journal of Respiratory and Critical Care Medicine, 199, A1046, 2019; Labeguere F. et al.: J. Med. Chem., 63(22), 13526-13545, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.