GLPG-3312

SI-7494

GLPG-3312, >98% (HPLC)

CAS No. : [2340388-72-7]

IUPAC Name : N-Cyclopropyl-2-(difluoromethoxy)-6-methoxy-4-(5-(1-methyl-1H-pyrazol-4-yl)-1H-benzo[d]imidazol-1-yl)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GLPG-3312 potently inhibits SIK1/2/3 with low‑nanomolar IC₅₀ values and shows strong anti‑inflammatory and immunomodulatory effects in cellular and animal systems. Its oral activity and broad SIK inhibition profile make it valuable for probing SIK‑dependent mechanisms in inflammation and immune regulation.

References : Temal-Laib T. et al.: J. Med. Chem., 67(1), 380-401, 2024.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.