Glumetinib

SI-8040

Glumetinib, >98% (HPLC)

CAS No. : [1642581-63-2]

Synonyms : Gumarontinib; SCC-244

IUPAC Name : 6-(1-Methyl-1H-pyrazol-4-yl)-1-((6-(1-methyl-1H-pyrazol-4-yl)imidazo[1,2-a]pyridin-3-yl)sulfonyl)-1H-pyrazolo[4,3-b]pyridine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Glumetinib is a potent and highly selective ATP‑competitive inhibitor of c‑MET, exhibiting an IC₅₀ of 0.42 nM. It maintains >2400‑fold selectivity over 312 kinases, notably RON and the homologous AXL, Mer, and TyrO3 kinases. Glumetinib effectively suppresses c‑MET‑driven oncogenic signaling and displays strong antitumor activity.

References : Ai J. et al.: Mol. Cancer Ther., 17(4), 751-762, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.