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GLUT inhibitor 1

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SI-6077

GLUT inhibitor 1, >98% (HPLC)

CAS No. : [2421141-40-2]

IUPAC Name : 2-(3-(4-((4-(1H-Pyrazol-4-yl)phenyl)amino)-6-cyclobutyl-5,6,7,8-tetrahydropyrido[4,3-d]pyrimidin-2-yl)phenoxy)-N-(1-methylcyclopropyl)acetamide

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Chemical Properites
Mol. Formula :
C32H35N7O2
Mol. Weight :
549.68
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GLUT inhibitor‑1 is a sub‑micromolar inhibitor of GLUT1 and GLUT3 (IC50 = 242 nM and 179 nM) with oral activity and metabolic‑pathway selectivity, making it a useful tool for studying tumor metabolism and immune‑driven disorders.

References : Liu K. G. et al.: J. Med. Chem., 63(10), 5201-5211, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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