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GNE-131

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SI-980

GNE-131, >98% (HPLC)

CAS No. : [1629063-81-5]

IUPAC Name : N-(7-((3r,5r,7r)-Adamantan-1-ylmethoxy)-6-cyclopropyl-[1,2,4]triazolo[4,3-a]pyridin-3-yl)cyclopropanesulfonamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MG135.00
Back Order  Estimated to ship on 04 October 2026
10MG235.00
Back Order  Estimated to ship on 04 October 2026
25MG425.00
Back Order  Estimated to ship on 04 October 2026
50MG695.00
Back Order  Estimated to ship on 04 October 2026
100MG1195.00
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C23H30N4O3S
Mol. Weight :
442.57
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GNE-131 is a potent, selective inhibitor of sodium channel NaV1.7 with IC50 of 3 nM, >80-fold selectivity over the cardiac sodium channel NaV1.5.

References : Focken T. et al.: J. Med. Chem., 61(11), 4810-4831, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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