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SI-7351
GNE-235, >98% (HPLC)
CAS No. : [3036574-72-5]
IUPAC Name : (S)-6-(Furan-2-yl)-4-(2-methylpyrrolidin-1-yl)pyridazin-3-amine
| Price And Availability | ||||
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| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C13H16N4O | Mol. Weight : 244.3 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : GNE‑235 selectively targets the second bromodomain of PBRM1 with sub‑micromolar affinity (Kᴰ = 0.28 ± 0.02 µM). This selectivity enables detailed investigation of PBRM1‑mediated chromatin remodeling and associated cellular processes.
References : Cochran A. G. et al.: J. Med. Chem., 66(18), 13116-13134, 2023.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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