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GNE-4997

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SI-4217

GNE-4997, >98% (HPLC)

CAS No. : [1705602-02-3]

MDL No. : MFCD31692422

Synonyms : N-(1-((1,1-Dioxidotetrahydro-2H-thiopyran-2-yl)(phenyl)methyl)-1H-pyrazol-4-yl)-5,5-difluoro-5a-methyl-1,4,4a,5,5a,6-hexahydrocyclopropa[f ]indazole-3-carboxamide

Price And Availability
Pack SizePrice in USDAdd To Shopping CartAvailabilityShipping Status
5MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
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25MGRequest A Quote
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50MGRequest A Quote
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100MGRequest A Quote
Back Order  Estimated to ship on 01 November 2026
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Note: GNE-4997 is not in stock but can be available through custom synthesis. The estimated lead-time is 8-10 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C25H27F2N5O3S
Mol. Weight :
515.58
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GNE-4997 is a potent and selective ITK inhibitor (ITK Ki = 0.09nM, PLCγ IC50 = 0.004 μM).

References : Burch D. J. et al.: J. Med. Chem., 58(9), 3806-3816, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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