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GNE-6776

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SI-6066

GNE-6776, >98% (HPLC)

CAS No. : [2009273-71-4]

IUPAC Name : 6'-Amino-4'-ethyl-5'-(4-hydroxyphenyl)-N-methyl-[3,3'-bipyridine]-6-carboxamide

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Chemical Properites
Mol. Formula :
C20H20N4O2
Mol. Weight :
348.41
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GNE‑6776 is a selective, orally bioavailable USP7 inhibitor, acting through non‑covalent allosteric inhibition of USP7 to block its deubiquitinase activity.

References : Kategaya L. et al.: Nature, 550(7677), 534-538, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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