GNE-781

SI-1905

GNE-781, 98% (HPLC)

CAS No. : [1936422-33-1]

MDL No. : MFCD31693834

IUPAC Name : 3-(7-(Difluoromethyl)-6-(1-methyl-1H-pyrazol-4-yl)-3,4-dihydroquinolin-1(2H)-yl)-N-methyl-1-(tetrahydro-2H-pyran-4-yl)-6,7-dihydro-1H-pyrazolo[4,3-c]pyridine-5(4H)-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	95.00		Back Order	Estimated to ship on 04 October 2026
10MG	125.00		Back Order	Estimated to ship on 04 October 2026
25MG	225.00		Back Order	Estimated to ship on 04 October 2026
50MG	425.00		Back Order	Estimated to ship on 04 October 2026
100MG	725.00		Back Order	Estimated to ship on 04 October 2026
250MG	1495.00		Back Order	Estimated to ship on 04 October 2026
500MG	2495.00		Back Order	Estimated to ship on 04 October 2026

Applications : GNE-781 is a highly potent and selective CBP inhibitor with an IC₅₀ of 0.94 nM in TR-FRET assay. GNE-781 also inhibits BRET and BRD4(1) with IC₅₀s of 6.2 nM and 5100 nΜ, respectively

References : Romero F. A. et al.: J. Med. Chem., 60(22), 9162-9183, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.