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GNE-7915 tosylate

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SI-6375

GNE-7915 tosylate, >98% (HPLC)

CAS No. : [2070015-00-6]

IUPAC Name : (4-((4-(Ethylamino)-5-(trifluoromethyl)pyrimidin-2-yl)amino)-2-fluoro-5-methoxyphenyl)(morpholino)methanone 4-methylbenzenesulfonate

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Chemical Properites
Mol. Formula :
C19H21F4N5O3 • C7H8O3S
Mol. Weight :
615.6
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GNE‑7915 tosylate retains the parent compound’s strong LRRK2 inhibition (IC50 = 9 nM) and confirmed brain penetration, making it a valuable tool for probing LRRK2‑dependent pathways in neurodegeneration research.

References : Kavanagh M. E. et al.: Bioorg. Med. Chem. Lett., 23(13), 3690-6, 2013; Estrada A. A. et al.: J. Med. Chem., 55(22), 9416-33, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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