GNE-9605

SI-8015

GNE-9605, >98% (HPLC)

CAS No. : [1536200-31-3]

IUPAC Name : N2-(5-Chloro-1-((3S)-3-fluoro-1-(oxetan-3-yl)piperidin-4-yl)-1H-pyrazol-4-yl)-N4-methyl-5-(trifluoromethyl)pyrimidine-2,4-diamine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GNE‑9605 is an orally active LRRK2 inhibitor with strong nanomolar potency (IC₅₀ = 18.7 nM). It inhibits Ser1292 autophosphorylation, a key marker of LRRK2 activity, making it a valuable tool compound for Parkinson’s disease research.

References : Estrada A. A. et al.: J. Med. Chem., 57(3), 921-36, 2014; Kumar S. et al.: Environ. Sci. Pollut. Res. Int., 29(22), 32368-32382, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.