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GNF-6702

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SI-8150

GNF-6702, >98% (HPLC)

CAS No. : [1799329-72-8]

IUPAC Name : N-(4-Fluoro-3-(6-(pyridin-2-yl)-[1,2,4]triazolo[1,5-a]pyrimidin-2-yl)phenyl)-2,4-dimethyloxazole-5-carboxamide

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Chemical Properites
Mol. Formula :
C22H16FN7O2
Mol. Weight :
429.42
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GNF-6702 selectively targets the kinetoplastid proteasome and shows potent antiparasitic activity in vivo. It effectively clears infections in murine models of leishmaniasis, Chagas disease, and African trypanosomiasis.

References : Nagle A. et al.: J. Med. Chem., 63(19), 10773-10781, 2020.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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