GNF-7

SI-8002

GNF-7, >98% (HPLC)

CAS No. : [839706-07-9]

IUPAC Name : N-(4-Methyl-3-(1-methyl-7-((6-methylpyridin-3-yl)amino)-2-oxo-1,4-dihydropyrimido[4,5-d]pyrimidin-3(2H)-yl)phenyl)-3-(trifluoromethyl)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GNF‑7 inhibits Bcr‑Abl signaling with low‑nanomolar potency against both WT and T315I forms and also targets ACK1 and GCK. This multikinase activity makes it valuable for probing oncogenic signaling pathways in hematologic cancer models.

References : Lu X. et al.: Bioorg. Med. Chem. Lett., 25(17), 3458-63, 2015; Choi H. G. et al.: J. Med. Chem., 53(15), 5439-48, 2010.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.