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Golvatinib

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SI-8047

Golvatinib, >98% (HPLC)

CAS No. : [928037-13-2]

Synonyms : E-7050

IUPAC Name : N-(2-Fluoro-4-((2-(4-(4-methylpiperazin-1-yl)piperidine-1-carboxamido)pyridin-4-yl)oxy)phenyl)-N-(4-fluorophenyl)cyclopropane-1,1-dicarboxamide

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Back Order  Estimated to ship on 04 October 2026
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We accept
Chemical Properites
Mol. Formula :
C33H37F2N7O4
Mol. Weight :
633.7
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Golvatinib is a dual c‑MET/VEGFR2 inhibitor with low‑nanomolar potency (IC50 = 14–16 nM). By concurrently suppressing MET signaling and VEGFR2‑dependent angiogenic pathways, it serves as a valuable tool for investigating tumor growth and metastatic mechanisms.

References : Nakagawa T. et al.: Cancer Sci., 101(1), 210-215, 2010; Wang W. et al.: Clin. Cancer Res., 18(6), 1663-1671, 2012.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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