GPX4-IN-4

SI-7290

GPX4-IN-4, >98% (HPLC)

CAS No. : [2920221-53-8]

IUPAC Name : Methyl (1S,3R)-2-(2-chloroacetyl)-1-(4-(methylsulfonyl)phenyl)-2,3,4,9-tetrahydro-1H-pyrido[3,4-b]indole-3-carboxylate

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 05 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 05 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 05 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 05 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 05 October 2026

Applications : GPX4‑IN‑4 is a potent glutathione peroxidase 4 (GPX4) inhibitor that induces ferroptotic cell death by blocking lipid peroxide detoxification. It serves as a useful tool compound for cancer research, enabling the study of GPX4‑dependent survival pathways, ferroptosis sensitivity, and synthetic‑lethal vulnerabilities in tumor models.

References : Randolph J. T. et al.: J. Med Chem., 66(6), 3852-3865, 2023.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.