Grazoprevir

SI-6072

Grazoprevir, >98% (HPLC)

CAS No. : [1350514-68-9]

Synonyms : MK-5172

IUPAC Name : (33R,35S,91R,92R,5S)-5-(tert-Butyl)-N-((1R,2S)-1-((cyclopropylsulfonyl)carbamoyl)-2-vinylcyclopropyl)-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : Grazoprevir is a potent HCV NS3/4A protease inhibitor with K_i values of 0.01–0.90 nM across major HCV genotypes. It also inhibits the SARS‑CoV‑2 3CL protease, highlighting its broader antiviral potential beyond hepatitis C.

References : Summa V. et al.: Antimicrob. Agents Chemother., 56(8), 4161-7, 2012; Harper S. et al.: ACS Med. Chem. Lett., 3(4), 332-6, 2012; Sun Q. et al.: Signal Transduct. Target Ther., 6(1), 212, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.