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Grazoprevir sodium salt

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SI-6074

Grazoprevir sodium salt, >98% (HPLC)

CAS No. : [1425038-27-2]

Synonyms : MK-5172 sodium salt

IUPAC Name : Sodium ((1R,2S)-1-((33R,35S,91R,92R,5S)-5-(tert-butyl)-17-methoxy-4,7-dioxo-2,8-dioxa-6-aza-1(2,3)-quinoxalina-3(3,1)-pyrrolidina-9(1,2)-cyclopropanacyclotetradecaphane-35-carboxamido)-2-vinylcyclopropane-1-carbonyl)(cyclopropylsulfonyl)amide

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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250MGRequest A Quote
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Chemical Properites
Mol. Formula :
C38H49N6O9S - • Na+
Mol. Weight :
788.89
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : Grazoprevir sodium salt is a potent HCV NS3/4A protease inhibitor with Ki values of 0.01–0.90 nM across major hepatitis C genotypes. It also inhibits the SARS‑CoV‑2 3CL protease, indicating additional antiviral potential beyond HCV.

References : Summa V. et al.: Antimicrob. Agents Chemother, 56(8), 4161-7, 2012; Harper S. et al.: ACS Med. Chem. Lett., 3(4), 332-6, 2012; Sun Q. et al.: Signal Transduct. Target Ther., 6(1), 212, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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