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GS-443902 trisodium

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SL-6022

GS-443902 trisodium, >98%

CAS No. : [1355050-21-3]

Synonyms : GS-441524 triphosphate trisodium; Remdesivir metabolite trisodium

IUPAC Name : Sodium ((2R,3S,4R,5R)-5-(4-aminopyrrolo[2,1-f][1,2,4]triazin-7-yl)-5-cyano-3,4-dihydroxytetrahydrofuran-2-yl)methyl hydrogen triphosphate

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Chemical Properites
Mol. Formula :
C12H13N5Na3O13P3
Mol. Weight :
597.15
Appearance :
Pale yellow solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GS-443902 trisodium is a potent viral RNA-dependent RNA-polymerases (RdRp) inhibitor. GS-443902 is an active triphosphate metabolite of Remdesivir.

References : Warren T. K. et al.: Nature 531(7594), 381-385, 2016; Agostini M. L. et al.: mBio 9(2), 6, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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