GS-444217

SI-6343

GS-444217, >98% (HPLC)

CAS No. : [1262041-49-5]

IUPAC Name : 4-(4-Cyclopropyl-1H-imidazol-1-yl)-N-(3-(4-cyclopropyl-4H-1,2,4-triazol-3-yl)phenyl)picolinamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GS‑444217 selectively inhibits ASK1 with sub‑nanomolar potency and demonstrates oral activity. Its ATP‑competitive mechanism makes it valuable for probing ASK1‑regulated inflammatory and stress‑signaling networks.

References : Liles J. T. et al.: J. Clin. Invest, 128(10), 4485-4500, 2018; Budas G. R. et al.: Am. J. Respir. Crit. Care Med., 197(3), 373-385, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.