GS-5759

SI-6719

GS-5759, >98% (HPLC)

CAS No. : [1346653-91-5]

IUPAC Name : (R)-6-((3-((4-(5-((2-Hydroxy-2-(8-hydroxy-2-oxo-1,2-dihydroquinolin-5-yl)ethyl)amino)pent-1-yn-1-yl)phenyl)carbamoyl)phenyl)sulfonyl)-4-((3-methoxyphenyl)amino)-8-methylquinoline-3-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GS‑5759 activates β₂‑adrenergic receptors to raise cAMP and relax airway smooth muscle, and concurrently inhibits PDE4 to sustain cAMP levels and suppress inflammation. This dual mechanism produces potent bronchodilation and anti‑inflammatory effects in animal studies, making GS‑5759 valuable for investigating COPD and related respiratory disorders.

References : Joshi T. et al.: J. Pharmacol. Exp. Ther., 360(2), 324-340, 2017; Salmon M. et al.: Pharmacol. Res. Perspect., 2(4), e00046, 2014.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.