GS-9716

SI-7924

GS-9716, >98% (HPLC)

IUPAC Name : N-((1S,12'S,16'S,16a'S,18a'R,E)-6-Chloro-12',16'-dimethyl-10'-oxido-8'-oxo-3,4,8',11',12',13',16',16a',17',18',18a',19'-dodecahydro-1'H,2H,3'H-10'λ6-spiro[naphthalene-1,2'-[5,7]ethenocyclobuta[i][1,4]oxazepino[3,4-f][1]thia[2,7]diazacyclohexadecin]-10'-yl)-3-methoxy-1-methyl-1H-pyrazole-4-carboxamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GS‑9716 is a potent, selective Mcl‑1 inhibitor. It blocks the anti‑apoptotic function of Mcl‑1, restoring apoptotic signaling in Mcl‑1–dependent tumors. GS‑9716 shows strong biochemical and cellular Mcl‑1 engagement, favorable drug‑like properties, and robust antitumor activity in preclinical models, making it a useful tool compound for studying Mcl‑1 biology and apoptosis‑driven cancer therapeutics.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.