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CAS No. : [2219362-41-9]
IUPAC Name : (R)-2-(tert-Butoxy)-2-(7-(4-chlorophenyl)-5-methyl-2-(1-methyl-3-(1-(oxetan-3-yl)piperidin-4-yl)-1H-indazol-5-yl)benzo[d]thiazol-6-yl)acetic acid
| Price And Availability | ||||
|---|---|---|---|---|
| Pack Size | Price in USD | Add To Shopping Cart | Availability | Shipping Status |
| 5MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 10MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 25MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 50MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
| 100MG | Request A Quote | Back Order | Estimated to ship on 04 October 2026 | |
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| Chemical Properites | |
|---|---|
Mol. Formula : C36H39ClN4O4S | Mol. Weight : 659.24 |
Appearance : Solid | Melting Point : Not available |
| For Laboratory research use only, not for drug, household or other uses. | |
Applications : GS‑9822 functions as a potent antiviral agent with nanomolar activity against wild‑type HIV‑1. It effectively blocks the LEDGF/p75–integrase interaction (IC50= 0.07 µM) and demonstrates high metabolic stability in vitro. In vivo, GS‑9822 exhibits advantageous oral pharmacokinetics with low systemic clearance in rats, dogs, and monkeys.
References :
Bruggemans A. et al.: Antimicrob. Agents Chemother., 65(5), e02328-20, 2023.
Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.
Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.
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