GSK-1059615

SI-7171

GSK-1059615, >98% (HPLC)

CAS No. : [958852-01-2]

IUPAC Name : (E)-4-((4-(Pyridin-4-yl)quinolin-6-yl)methylene)thiazolidine-2,5-dione

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GSK-1059615 reversibly inhibits PI3Kα/β/δ/γ with sub‑nanomolar to low‑nanomolar potency and also targets mTOR (IC₅₀= 12 nM). Its dual‑pathway activity makes it a valuable tool for studying PI3K/mTOR‑driven signaling and disease biology.

References : Carnero A. et al.: Expert. Opin. Investig. Drugs, 18(9), 1265-77, 2009; Xie J. et al.: Oncotarget. 8(31), 50814-50823, 2017; Leontieva O. V. et al.: Aging (Albany NY)., 8(12), 3535-3551, 2016; Hong J. et al.: Biol. Reprod., 97(5), 671-687, 2017.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.