GSK-1070916

SI-4890

GSK-1070916, >98% (HPLC)

CAS No. : [942918-07-2]

MDL No. : MFCD22420815

Synonyms : GSK1070916

IUPAC Name : 3-(4-(4-(2-(3-((Dimethylamino)methyl)phenyl)-1H-pyrrolo[2,3-b]pyridin-4-yl)-1-ethyl-1H-pyrazol-3-yl)phenyl)-1,1-dimethylurea

Price And Availability
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5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : GSK-1070916 is a reversible and ATP-competitive inhibitor of aurora B/C with IC₅₀ of 3.5 nM/6.5 nM. It displays >100-fold selectivity against the closely related aurora A-TPX2 complex.

References : Anderson K. et al.: Biochem J. 420(2), 259-265,2009; Hardwicke M. A. et al.: Mol Cancer Ther, 8(7),1808-1817, 2009; Moy C. et al.: J. Transl Med., 9, 110, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.