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GSK-2292767

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SI-5160

GSK-2292767, >98% (HPLC)

CAS No. : [1254036-66-2]

MDL No. : MFCD22572737

IUPAC Name : N-(5-(4-(5-(((2R,6S)-2,6-Dimethylmorpholino)methyl)oxazol-2-yl)-1H-indazol-6-yl)-2-methoxypyridin-3-yl)methanesulfonamide

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Chemical Properites
Mol. Formula :
C24H28N6O5S
Mol. Weight :
512.59
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GSK-2292767 is a potent and selective inhibitor of PI3Kδ, with a pIC50 of 10.1. GSK-2292767 showing greater than 500-fold selective over the other PI3K isoforms. GSK-2292767 can be used for the research of respiratory disease.

References : Down K. et, al.: J. Med Chem., 58(18), 7381-99, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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