GSK-2324

SI-8158

GSK-2324, >98% (HPLC)

CAS No. : [1020567-30-9]

IUPAC Name : 6-(4-((3-(2,6-Dichlorophenyl)-5-isopropylisoxazol-4-yl)methoxy)phenyl)quinoline-2-carboxylic acid

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Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
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Applications : GSK-2324 activates FXR with an EC₅₀ of 120 nM and shows consistent in vivo stability, with t_1/2 values ranging from 84 to 170 min across mouse, rat, beagle, and cyno. These properties make it a useful tool compound for probing FXR‑regulated pathways in diabetes research.

References : Bass Y. J. et al.: Bioorg. Med. Chem. Lett., 21(4), 1206-13, 2011.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.