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GSK-2578215A

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SI-6373

GSK-2578215A, >98% (HPLC)

CAS No. : [1285515-21-0]

IUPAC Name : 2-(Benzyloxy)-5-(2-fluoropyridin-4-yl)-N-(pyridin-3-yl)benzamide

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25MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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250MGRequest A Quote
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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C24H18FN3O2
Mol. Weight :
399.43
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GSK-2578215A selectively inhibits LRRK2 with low‑nanomolar potency and shows equivalent activity toward the wild‑type and G2019S mutant forms. It is widely used as a tool compound for probing LRRK2‑dependent signaling pathways.

References : Reith A. D. et al.: Bioorg. Med. Chem. Lett., 22(17), 5625-9, 2012. Saez-Atienzar S. et al.: Cell Death Dis., 5(8), e1368, 2014; Chen. L. et al.: Clin. Transl. Med., 11(3), e341, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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