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GSK-26366771

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SI-5327

GSK-26366771, >98% (HPLC)

CAS No. : [1372540-25-4]

MDL No. : MFCD22417098

IUPAC Name : 1-(2-Methyl-3-(trifluoromethyl)benzyl)-6-morpholino-1H-benzo[d]imidazole-4-carboxylic acid

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Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C21H20F3N3O3
Mol. Weight :
419.40
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GSK2636771 is a potent, orally bioavailable and selective inhibitor of PI3Kβ with >900-fold selectivity over PI3Kα/PI3Kγ and >10-fold over PI3Kδ. Sensitive to PTEN null cell lines.

References : Macauley D. et al.: Drugs Fut., 37(6), 451, 2012; Weigelt B. et al.: Clin Cancer Res., 19(13), 3533-3544, 2013; Leroy C. et al.: Breast Cancer Res., 18(1), 41, 2016.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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