GSK-2646264

SI-6327

GSK-2646264, >98% (HPLC)

CAS No. : [1398695-47-0]

IUPAC Name : 7-(2-Methoxy-6-((4-methylpyridin-2-yl)methoxy)phenyl)-2,3,4,5-tetrahydro-1H-benzo[d]azepine

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GSK-2646264 is a potent SYK inhibitor (pIC₅₀= 7.1) with defined off‑target activity across several kinases, including LCK, LRRK2, GSK3β, JAK2, VEGFR2, Aurora B, and Aurora A. It readily penetrates the epidermis and dermis, making it suitable for studies involving cutaneous SYK signaling.

References : Barker M. D. et al.: Bioorg. Med. Chem. Lett., 28(21), 3458-3462, 2018; Molina C. R. et al.: Br. J. Pharmacol., 176(8), 1135-1142, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.