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GSK-2879552

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SI-6185

GSK-2879552, >98% (HPLC)

CAS No. : [1401966-69-5]

IUPAC Name : 4-((4-((((1R,2S)-2-Phenylcyclopropyl)amino)methyl)piperidin-1-yl)methyl)benzoic acid

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Chemical Properites
Mol. Formula :
C23H28N2O2
Mol. Weight :
364.49
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GSK-2879552 is a potent, irreversible LSD1/KDM1A inhibitor with good oral activity. Through sustained inhibition of LSD1‑mediated chromatin remodeling, it exhibits antitumor potential in preclinical studies.

References : Huang M. et al.: Cancer Lett., 398, 12-21, 2017; Mohammad H. P. et al. Cancer Cell, 28(1), 57-69, 2015.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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