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GSK-3145095

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SI-5721

GSK-3145095, >98% (HPLC)

CAS No. : [1622849-43-7]

IUPAC Name : (S)-5-Benzyl-N-(7,9-difluoro-2-oxo-2,3,4,5-tetrahydro-1H-benzo[b]azepin-3-yl)-1H-1,2,4-triazole-3-carboxamide

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5MGRequest A Quote
Back Order  Estimated to ship on 04 October 2026
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Chemical Properites
Mol. Formula :
C20H17F2N5O2
Mol. Weight :
397.39
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GSK-3145095 is a RIP1 kinase inhibitor with an IC50 of 6.3 nM. GSK3145095 is a clinical candidate for the potential treatment of cancer.

References : Harris P. A. et al.: ACS Med Chem Lett., 10(6), 857-862, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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