GSK-3186899

SI-3403

GSK-3186899, >98% (HPLC)

CAS No. : [1972617-87-0]

Synonyms : DDD-853651

IUPAC Name : 3,3,3-Trifluoro-N-(trans-4-((3-((S)-2-methylmorpholino)-1Hpyrazolo[3,4-d]pyrimidin-6-yl)amino)cyclohexyl)propane-1-sulfonamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
Note: GSK-3186899is not in stock but can be available through custom synthesis. The estimated lead-time is 4-6 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us at sales@syninnova.com or Request A Quote. We respond promptly. Thank You!

Applications : GSK-3186899 is a novel specific inhibitor of parasite cdc-2-related kinase 12 (CRK12), shows activity against L. donovani in intra-macrophage assay with EC₅₀ value of 1.4 uM, and shows good selectivity against mammalian THP-1 host cells (EC₅₀> 50 uM).

References : Thomas G. M. et al.: J. Med. Chem., 62(3), 1180-1202, 2019.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.