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GSK-3395879

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SI-1236

GSK-3395879, >98% (HPLC)

CAS No. : [2215852-91-6]

Synonyms : GSK3395879

IUPAC Name : 4-(((3S,4R)-1-((2-Cyano-4-(trifluoromethyl)phenyl)sulfonyl)-4-hydroxy-4-(hydroxymethyl)pyrrolidin-3-yl)oxy)-2-fluorobenzonitrile

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Note: GSK-3395879 is not in stock but can be available through custom synthesis. The estimated lead-time is 8-10 weeks. The product will be characterized by NMR and Mass analysis. Purity (HPLC) is usually >98%. COA, QC data and SDS will be provided along with the product. For information on pricing and availability please contact us atsales@syninnova.com or Request A Quote. We respond promptly. Thank You!
Chemical Properites
Mol. Formula :
C20H15F4N3O5S
Mol. Weight :
485.41
Appearance :
White solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GSK-3395879 is a novel potent, selective, orally bioavailable antagonist of TRPV4 with IC50 of 1 nM (hTRPV4).

References : Brnardic J. E. et al.: J. Med. Chem., 61(21), 9738-9755, 2018.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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