GSK-3739936

SI-7020

GSK-3739936, >98% (HPLC)

CAS No. : [1803444-21-4]

Synonyms : BMS-986180

IUPAC Name : (S)-2-(tert-Butoxy)-2-(4-(4,4-dimethylpiperidin-1-yl)-5-(4-(4-fluorophenethoxy)phenyl)-2,6-dimethylpyridin-3-yl)acetic acid

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
250MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
500MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GSK-3739936 functions as a potent HIV‑1 allosteric integrase inhibitor with nanomolar activity (IC₅₀ = 11.1 nM; EC₅₀ = 1.7 nM). It is a weak inhibitor of CYP enzymes (IC₅₀> 24.3 µM) and demonstrates strong pharmacokinetic performance in preclinical species, including fast absorption, low–moderate clearance, and high oral bioavailability.

References : Naidu B. N. et al.: J. Med. Chem., 65(6), 4949-4971, 2022.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.