GSK-452

SI-6223

GSK-452, >98% (HPLC)

IUPAC Name : N-Ethyl-3-(1-methyl-1H-1,2,3-triazol-4-yl)-4-((6-methylpyridin-2-yl)methoxy)benzamide

Price And Availability
Pack Size	Price in USD	Add To Shopping Cart	Availability	Shipping Status
5MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
10MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
25MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
50MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026
100MG	Request A Quote		Back Order	Estimated to ship on 04 October 2026

Applications : GSK‑452 is a potent, BD2‑selective BET inhibitor that preferentially targets BRD2, offering a focused epigenetic mechanism distinct from pan‑BET inhibitors. It shows strong BD2 selectivity, robust modulation of BD2‑dependent transcription, and is used as a tool compound for probing BET‑regulated pathways in oncology and inflammation.

References : Aylott H. E. et al.: J. Med. Chem., 64(6), 3249-3281, 2021.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.