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GSK-5498A

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SI-6873

GSK-5498A, >98% (HPLC)

CAS No. : [1253186-49-0]

IUPAC Name : 2,6-Difluoro-N-(1-(2-fluoro-6-(trifluoromethyl)benzyl)-1H-pyrazol-3-yl)benzamide

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Chemical Properites
Mol. Formula :
C18H11F6N3O
Mol. Weight :
399.3
Appearance :
Solid
Melting Point :
Not available
For Laboratory research use only, not for drug, household or other uses.

Applications : GSK‑5498A is a selective CRAC channel inhibitor (IC50 = 1 µM) that suppresses mediator release from mast cells and pro‑inflammatory cytokine production from T cells. It is used in research on inflammatory disorders.

References : Rice L. V. et al.: Eur. J. Pharmacol., 704(1-3):49-57. 2013.

Storage : Keep container tightly closed under nitrogen or argon and refrigerate for long-term shelf life.

Caution : In case of contact with skin or eyes, rinse immediately with plenty of water and seek medical advice. Wear suitable protective clothing and gloves.

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